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April 2020

Webinar: An Introduction to Liquid Chromatography-Mass Spectrometry for the Clinical Laboratory

April 1 @ 8:00 am - 9:00 pm PDT

"The capabilities of liquid chromatography coupled to mass spectrometry make the technology a very attractive tool in clinical laboratory settings. However, not all laboratorians have a basic understanding of clinical mass spectrometry. In this presentation, the fundamentals of liquid chromatography and mass spectrometry will be briefly discussed. Further, a liquid chromatography-mass spectrometry assay validation will be reviewed.

Learning Objectives:
1. List the basic components of a liquid chromatograph and mass spectrometer.
2. Recognize the benefits of liquid chromatography-mass spectrometry to the clinical laboratory."

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Clinical Management of Critically Ill Adults with COVID-19

April 2 @ 2:00 pm - 3:00 pm EDT

"During this COCA Call, clinicians will provide an overview of the clinical characteristics of COVID-19 patients, including case presentations of critically ill adults and clinical management challenges, and summarize recently published guidelines on clinical management of critically ill adults."

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Help Validate and Verify Laboratory Developed Tests: Using EP19, A Framework for Using CLSI Documents

April 7 @ 1:00 pm - 2:00 pm EDT

"During the webinar, you will learn:

* The measurement procedure life cycle phase.
* What testing you need to do to validate your laboratory-developed test (LDT) to ensure it is working properly.
* What testing you need to do to verify a new manufacturer's test and ensure it is working properly in your laboratory.
* How EP19-Ed2 (free) can help."

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Webinar: Strategies to achieve robustness in clinical proteomics research

April 9 @ 11:00 am - 12:00 pm EDT

"Mass spectrometry-based proteomics allows the simultaneous measurement of a large number of proteins and has been widely used for protein biomarker discovery and validation. Quantitative proteomics techniques were primarily developed with small sample numbers, but research involving clinical cohorts requires robust quantitation over a large number of samples. To ensure data accuracy, additional technical and analytical quality control measures need to be implemented in proteomics research involving clinical research cohorts. This webinar will discuss the key considerations and suggest some strategies that has proved useful in clinical research study design."

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Webinar – Benchling for Lab Automation: Harness the full potential of your lab hardware

April 14 @ 11:00 am - 12:00 pm PDT

Let’s face it: lab automation doesn’t always feel so automated. Manual run instructions, manipulation of CSV outputs, monthslong configuration updates... Who would’ve guessed the “lab of the future” would involve so much inefficiency?

Benchling for Lab Automation is how biotechs like Regeneron and Recursion Pharmaceuticals orchestrate their instruments, automatically feed results into their informatics systems, and save 10 hours per run — no inefficient busywork necessary.

In this webinar, we'll give you a firsthand look at how Benchling for Lab Automation can help you increase experimental scale, enhance R&D productivity, improve data integrity, and derive deeper experimental insights.

Apr 14, 2020 11:00 AM in Pacific Time (US and Canada)
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Webinar: Developments in STD Testing – a Collaborative Discussion for Clinicians and Laboratorians

April 15 @ 12:00 pm - 1:00 pm CDT

"This cross-cutting webinar hosted collaboratively by Health Care Education and Training (HCET) and the Wisconsin State Laboratory of Hygiene (WSLH) will discuss the concerning rise in STD rates and ways clinicians and laboratorians can work together to combat this problem. You will hear about the importance of looking beyond traditional testing and evaluating patients for disease at extragenital sites or from newly recognized pathogens like Mycoplasma genitalium. This webinar will provide information on the latest laboratory options for this kind of testing. Many of these assays have recently been FDA cleared or are coming soon to existing STD testing platforms.

A certificate of participation will be granted to each participant based on 1.0 contact hours of instruction toward credit."

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Webinar: Research Context and Research Chemistry: Information Literacy, Scholarly Publishing, and Data Management in the Chemistry Curriculum

April 16 @ 11:00 am - 12:00 pm EDT

"Exponential growth in the number of chemistry publications produced each year has made sorting through research topics increasingly difficult. This growth does have the advantage of exposing some of the flaws in the publication process that future chemists might be able to improve. Issues such as lack of reproducibility, overemphasis on citation metrics, data falsification, and predatory journals will have to be addressed by the next generation of scientists. To that end a new type of chemical literature course in the undergraduate and graduate curricula at Vanderbilt University is being introduced. This course will be divided into three sections.

The first half will focus on information seeking and literacy by covering contentious topics within chemistry (e.g., fracking, nuclear energy, thalidomide, and research related to the supposed vaccine/autism link) and teaching students about the databases and techniques that can help them identify trustworthy information.

The second portion will focus on the history, present, and future of scholarly publishing. Students will learn about current practices by hearing from a journal editor and an acquisition librarian that frequently negotiates with publishers.

The final portion will be on data management as a potential solution to some of the issues with publishing. Students will learn how to manage, find, store, and share data related to their research. Other scientific literature or information curricula will be compared to this course by distributing a survey to faculty and staff at colleges and universities and student learning will be assessed by using a pre/post test to determine their confidence and comfort with finding, describing, publishing, and sharing research articles and data."

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Webinar: AI and Workflow Orchestration

April 21 @ 1:00 pm - 2:00 pm EDT

"After building a model and validating it in an external dataset, it’s time to put it into practice. What is the best way to use it? Should it notify physicians as soon as the inferences are done? Should it notify radiologists? Or is a worklist prioritization the best way to use the model outputs? In the case of automated segmentation, we can also send back results to be viewed in the PACS. Should this result be instantaneously available for every study, or, should the radiologist request these results for specific cases? There is likely not a correct answer that is best in all cases, but there are definitely better options for each kind of model."

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Webinar: Part 3 of 4: Inside the ‘Black Box’ of an Environmental Testing Laboratory – Basic Analytical Procedures

April 21 @ 1:30 pm - 2:30 pm EDT

"Eurofins TestAmerica is offering this 4 Part Webinar Series to review the basic tenants for a project team to interface and communicate with an environmental testing laboratory to execute a successful sampling project. These webinars are offered as an additional tool to support individuals who may be starting their career in the environmental field and will be interfacing with an environmental testing laboratory. These webinars are also appropriate for the seasoned professional who may be looking for a refresher in this area. This 4 Part Webinar Series can be viewed individually or as a series."

Part 3: What you will learn:

* Who writes and published analytical methods and where can I find them?
* What items should be considered during the method selection process?
* When and what should I communicate to the lab?
* What methods are available and what are the differences?
* What information is documented in the case narrative?
* What is the final deliverable?

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Webinar: Analytical Quality Control for the Pharmaceutical Industry

April 23 @ 9:00 am - 10:00 am PDT

"Analytical quality control refers to all those processes and procedures designed to ensure that the results of laboratory analysis are consistent, comparable, accurate and within specified limits. Quality control begins with sample collection and ends with the reporting of data. It is achieved through laboratory control of analytical performance.

This presentation will discuss Analytical Quality Control for pharmaceuticals as it relates to pipetting, weighing, sample collection and preparation, as well as analytical method and equipment qualification.

We will examine best practices to provide thoughts and ideas to develop or improve the performance of your current system. This presentation will help attendees understand the instrument qualification and system validation process and will provide instruction on how to prepare for audits and how to become FDA compliant."

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Webinar: Revolutionizing research: An EHR-enabled Learning Health Network

April 23 @ 1:00 pm - 2:00 pm EDT

"Widespread adoption of the EHR has led to a proliferation of the quantity of digitized health care data, but these data have not always translated into improved data quality. Despite increasing interest in using “real-world data” to power clinical research, most clinical trials and research protocols still rely on time-intensive, manual data entry. The power of the EHR remains largely untapped in clinical research. In this webinar, Dr. Ann Marie Navar and Dr. Eric Peterson, researchers at the Duke Clinical Research Institute and strategic advisors to Cerner Corp., will present an overview of their research using EHR data from multiple, connected health systems. They will also present their work with Cerner to build an EHR-enabled network to streamline clinical research conducted across multiple institutions, the Learning Health Network."

NOTE: Free for AMIA members and non-members

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Webinar: Modeling Human Disease: Tools for Cell & Tissue Culture

April 23 @ 1:00 pm - 2:00 pm EDT

"Cell and tissue culture are necessary for modeling human disease, but they come with many challenges. These techniques are often time-consuming and contamination, pipetting accuracy, and environmental variability can all impact your experimental results. Choosing the right tools—incubators, biological safety cabinets, and pipetting instruments—can help you overcome these challenges. Join Lab Manager and our panel of experts as we discuss some of the latest technology for cell and tissue culture and how they’re changing the way human disease is modeled."

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Webinar: Metals Analysis Evolution: Basic Principles to the Latest in Trace Metals, Part 1 – Basic Principles

April 28 @ 1:30 pm - 2:30 pm EDT

"This is the first Webinar in a series on Metals Analysis. We will discuss the historical development of analytical techniques for metals analysis in environmental chemistry, including flame atomic adsorption (AA), graphite furnace AA, inductively coupled plasma (ICP) with optical emission spectroscopy, and ICP mass spectrometry(ICPMS). Techniques and methods typically used today for routine metals analysis will be presented. Pros and cons of the instrumental techniques will be discussed, along with basic principles and typical performance criteria. Limitations of routine methods and techniques for overcoming them will be presented in subsequent Webinars.

Topics The Presentation Will Cover Include:

* General Overview of analytical techniques for metals analysis
* Pros and Cons of instrumental techniques
* Routine ICP-OES and ICPMS techniques – strengths and weaknesses
* Review of EPA methods (SW-846 Methods & EPA Office of Water Methods)"

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Right First Time LIMS Implementations: The Importance of Preplanning

April 29 @ 2:00 pm - 3:00 pm EDT

Join us Wednesday, April 29th at 2 pm EDT

So you have developed your user requirements, selected your LIMS product, and secured your project funding – now what? A critical step that is frequently overlooked is detailed preplanning for your LIMS project. Only with meticulous preplanning can you expect to deliver your LIMS implementation right, the first time.

In one hour, learn what preplanning entails, along with the skills and experience required to accomplish it.  This includes how organizational readiness plays into the phasing of your project, as well as how to get users what they need when they need it. When executed properly, LIMS implementation preplanning leads to early buy-in from all stakeholders, reduces project re-work, provides faster completion cycles, and maximizes end-user adoption.

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Webinar: 2020 – A Look at the State of Distributed Ledger Technology (aka Blockchain) in Healthcare

April 30 @ 1:00 pm - 2:00 pm CDT

"Analysts touted 2018 as the “Year of Blockchain in Healthcare”. It’s 2020 and that didn’t really happen. Starting with the Department of Health and Human Services’ “Blockchain Challenge” in 2016, there was a deluge of potential scenarios and solutions but the industry struggled to prove and implement the value of Distributed Ledger Technology (DLT)/Blockchain at scale. Fast forward to 2020 where we are facing increasing costs and the need for new therapies in the healthcare and life sciences supply chain. We now have more mature business value driven solutions with more mature technology. We have a better understanding of where real value exists that will not only reduce costs but enable care transformation and improved outcomes with accelerated drug development timelines.

In this webinar we’ll explore what’s different now and what the combination of new healthcare and life sciences needs and solutions can look like in 2020 and beyond leveraging DLT/Blockchain."

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