Neonatal lupus erythematosus

Neonatal lupus erythematosus is the occurrence of systemic lupus erythematosus (SLE) symptoms in an infant born from a mother with SLE, most commonly presenting with a rash resembling subacute cutaneous lupus erythematosus, and sometimes with systemic abnormalities such as complete heart block or hepatosplenomegaly.[1]

The infants have no skin lesions at birth, but sometimes develop them during the first weeks of life.[2] Neonatal lupus is usually benign and self-limited.[1]

It is associated with mothers who carry the Anti-SSA/Ro antibodies, which is associated most closely with the subacute cutaneous lupus erythematosus form of the disease.[2]

See also


  1. ^ a b > neonatal lupus Citing: Dorland's Medical Dictionary for Health Consumers. Copyright 2007
  2. ^ a b James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. Page 160. ISBN 0-7216-2921-0.

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