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THJ-018
Legal status
Legal status	CA: Schedule II; DE: Anlage II (Authorized trade only, not prescriptible); UK: Class B;
Identifiers
	IUPAC name 1-Naphthalenyl(1-pentyl-1H-indazol-3-yl)-methanone;
CAS Number	1364933-55-0 ;
ChemSpider	29341702;
UNII	B39WNG6743;
CompTox Dashboard (EPA)	DTXSID901010031 ;
Chemical and physical data
Formula	C23H22N2O
Molar mass	342.442 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(C1=NN(CCCCC)C2=C1C=CC=C2)C3=C4C(C=CC=C4)=CC=C3;
	InChI InChI=1S/C23H22N2O/c1-2-3-8-16-25-21-15-7-6-13-20(21)22(24-25)23(26)19-14-9-11-17-10-4-5-12-18(17)19/h4-7,9-15H,2-3,8,16H2,1H3; Key:VAKGBPSFDNTMDJ-UHFFFAOYSA-N;

THJ-018 (SGT-17) is a synthetic cannabinoid that is the indazole analogue of JWH-018 and has been sold online as a designer drug.^[1]^[2]

Pharmacology

THJ-018 acts as a full agonist with a binding affinity of 5.84 nM at CB₁ and 4.57 nM at CB₂ cannabinoid receptors.^[3]

THJ-018 is an Anlage II controlled drug in Germany.^[4] It is also banned in Sweden.^[5]

Legal status

Legal status	CA: Schedule II DE: Anlage II (Authorized trade only, not prescriptible) UK: Class B
Identifiers
IUPAC name 1-Naphthalenyl(1-pentyl-1H-indazol-3-yl)-methanone
CAS Number	1364933-55-0^Y
ChemSpider	29341702
UNII	B39WNG6743
CompTox Dashboard (EPA)	DTXSID901010031
Chemical and physical data
Formula	C₂₃H₂₂N₂O
Molar mass	342.442 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(C1=NN(CCCCC)C2=C1C=CC=C2)C3=C4C(C=CC=C4)=CC=C3
InChI InChI=1S/C23H22N2O/c1-2-3-8-16-25-21-15-7-6-13-20(21)22(24-25)23(26)19-14-9-11-17-10-4-5-12-18(17)19/h4-7,9-15H,2-3,8,16H2,1H3 Key:VAKGBPSFDNTMDJ-UHFFFAOYSA-N