Leveraging Cloud Technology to Manage Processes and Data to Maintain High-Quality Storage Services at The University of Sheffield Biorepository

Leveraging Cloud Technology to Manage Processes and Data to Maintain High-Quality Storage Services at The University of Sheffield Biorepository


Abstract:

Founded in 2009, the Biorepository at The University of Sheffield is critical for the progress of health-related research. They provide storage services and high-quality human biological samples to research groups for supporting cutting-edge investigation in the areas of oncology and human metabolism; infection, immunity and cardiovascular disease; and neuroscience.

The Sheffield Biorepository processes and stores about 300,000 human biological samples such as blood (buffy coat, serum, plasma), urine, saliva, tissue, histological slides and their associated data [Fig.1]. These samples are stored for two purposes: firstly, for use in future research projects, and secondly, before a research project has obtained ethical approval. Maintaining the biographic information for tens of samples each day—through every sample’s life cycle—using spreadsheets was becoming error-prone. Meticulous record-keeping is essential for each and every stored sample in order to serve customer demands on time. The data on human samples is to be kept confidential as per university and regulatory compliance standards. To overcome these challenges, a reliable and cost effective laboratory information management system (LIMS) was seen as a key requirement.

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