PCR and Diagnostics: COVID-19 Pandemic Reveals Serious Issues

PCR and Diagnostics: COVID-19 Pandemic Reveals Serious Issues

There has been recent discussion of the lack of accuracy of COVID-19 tests – both virus (rRT-PCR), which has been widely regarded as “the gold standard”, and antibody assays. The issue with PCR is not with the methods themselves, but the degree of human error that creeps in due to the complexity of the workflow – including pre-analytical sample handling, which can account for up to 68% of errors according to a recent paper, with overall inaccuracies of up to 41%.

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