Thermo Unveils New Proteomics Capabilities that Improve Quantitation and Characterization
Thermo Electron Corporation, the world leader in analytical instrumentation, unveils several new additions to its Proteomicsn suite of solutions. These include Thermo’s novel LTQ Orbitrap™ hybrid mass spectrometer, new techniques for peptide fragmentation and software for data interpretation, all which dramatically enhance and expand the potential for protein identification and quantification. The Proteomicsn suite is being showcased on Thermo’s booth #112, 114 & 116 at ABRF 2006, Long Beach Convention Center, Long Beach, California, Feb 11-14.
Thermo’s Proteomicsn solutions are designed to leverage the unmatched performance, speed, sensitivity and accuracy of their market-leading ion trap mass spectrometers for definitive quantitation of protein mixtures. Some of these new solutions include the LTQ Orbitrap, the first commercial mass analyzer based on an entirely new detection principle to be introduced to the market in over 20 years. This hybrid instrument greatly improves protein characterization, accelerates protein database searches and reduces false identification rates.
Thermo has also introduced several new approaches to protein quantitation, such as Pulsed-Q Dissociation (PQD), a new fragmentation technique that eliminates the low mass cut-off for ion traps and allows quantitation with iTRAQ™ labeling reagents. iTRAQ is a stable isotope method for relative protein quantitation using mass spectrometry.
In addition, BioWorks™ software has been extended to facilitate the use of all major protein quantitation techniques, namely SILAC (Stable Isotope Labeling with Amino Acids in Cell Culture), metabolic labeling, iTRAQ and ICAT (Isotope Coding Affinity Tagging). As a result, SEQUEST protein identifications can now easily be combined with quantitative data for an accurate view of protein expression levels.
For more information about Thermo’s Proteomicsn suite of products, please visit Thermo’s booth #112, 114 & 116 at ABRF 2006 in Long Beach, California. Alternatively, please call +1 800-532-4752, e-mail analyze@thermo.com or visit www.thermo.com/proteomics .
About Chromatography and Mass Spectrometry
A market leader in ion trap, hybrid, magnetic sector mass spectrometers, and hyphenated multi-instrument combinations of these products, Thermo’s integrated solutions include state-of-the-art instrument systems, advanced software and HPLC column technology with a wide range of innovative phases and hardware designs – tailored to meet the rigorous demands of lab professionals in applications such as proteomics, drug discovery, environmental analysis and analytical quantification. For more information, visit www.thermo.com/ms .
About Thermo Electron Corporation
Thermo Electron Corporation is the world leader in analytical instruments. Our instrument solutions enable our customers to make the world a healthier, cleaner and safer place. Thermo’s Life and Laboratory Sciences segment provides analytical instruments, scientific equipment, services and software solutions for life science, drug discovery, clinical, environmental and industrial laboratories. Thermo’s Measurement and Control segment is dedicated to providing analytical instruments used in a variety of manufacturing processes and in-the-field applications, including those associated with safety and homeland security.
