Simulations Plus Releases Major Upgrade to ClassPharmer™ Software

LANCASTER, Calif.–(BUSINESS WIRE)–Simulations Plus, Inc. (AMEX:SLP), a leading provider of simulation and modeling software for pharmaceutical discovery and development, announced that it has released a major upgrade to its best-in-class discovery cheminformatics ClassPharmer software for pharmaceutical research and development.

Dr. David Miller, team leader for discovery cheminformatics for Simulations Plus, said: In this upgrade, weve included a number of features requested by our users around the world, as well as extensions to the molecule design capability we released in the spring with the R-Table Exploder. Molecule design can now go beyond the chemistry represented in an R-Table to include a series of chemical reactions that can be used to create new molecules from scratch, or to create variations of existing molecules through a set of specific chemical reactions specified by the user. Combined with our ADMET Predictor software, this provides chemists with an ultra high throughput method for creating and screening new lead molecules.

Walt Woltosz, chairman and chief executive officer for Simulations Plus, added: Weve been showing how ClassPharmer and ADMET Predictor can be used together to speed up discovery chemistry. Last week, I co-chaired a scientific session and gave a presentation to a very large group of scientists from around the world at the International Society for the Study of Xenobiotics conference in Sendai, Japan. Weve had a number of requests for copies of the presentation slides since then. Weve continued to show these programs at pharmaceutical industry sites in Japan this week with excellent response, and well also be giving two seminars this week, one in Tokyo and one in Osaka, at which multiple companies will attend. Were excited about the response weve been getting from chemists for this new capability in drug design. The combination of ADMET Predictor and ClassPharmer is quite powerful, and each program should help to promote additional licenses of the other.

About Simulations Plus, Inc.

Simulations Plus, Inc., is a premier developer of groundbreaking drug discovery and development simulation and modeling software, which is licensed to and used in the conduct of drug research by major pharmaceutical and biotechnology companies worldwide. The Company has two other businesses, Words+, Inc. and FutureLab, which are based on its proprietary software technologies. Simulations Plus, Inc., is headquartered in Southern California. For more information, visit our Web site at www.simulations-plus.com.