Accelrys Announces Comprehensive, Multi-Year Agreements with Several Industry-Leading Pharmaceutical Companies

Accelrys, Inc., including its wholly owned subsidiary, Scitegic, Inc., announced today that it entered into a number of comprehensive, multi-year agreements with some of the world’s largest pharmaceutical companies during its third fiscal quarter ended December 31, 2005. These multi-year agreements, which include licenses for the Company’s industry-leading computational science software and informatics platform, have durations of two to five years and represent an aggregate dollar value of $29 million over the term of the agreements. This amount represents the highest aggregate dollar value ever attributable to multi-year agreements signed by the Company in any single fiscal quarter in the Company’s history.

“I am very pleased to report that our efforts to modernize our architecture and improve product quality, along with an intense focus on customer satisfaction, have successfully led to the signing of a number of comprehensive, multi-year agreements with our customers,” said Mark J. Emkjer, President and Chief Executive Officer of the Company. Mr. Emkjer concluded, “We believe that the collective magnitude of these agreements and their duration validate the significant value that our solutions bring to our customers.”

About Accelrys

Accelrys, Inc. (NASDAQ:ACCL) is a leading provider of software for computation, simulation, and the management and mining of scientific data used by biologists, chemists and materials scientists, including nanotechnology researchers, for product design as well as drug discovery and development. Scitegic, Inc., a wholly owned subsidiary of Accelrys, has pioneered a new technology platform called “data pipelining” to process research discovery data with unprecedented flexibility. Accelrys technology and services are designed to meet the needs of today’s leading research organizations. The company is headquartered in San Diego, California. Its materials research and development team is based at its European Headquarters and Centre of Excellence in Cambridge, UK. For more information about Accelrys, visit its website at http://www.accelrys.com