Bioinformatics & Cancerinformatics
Cambridge Healthtech Institute’s Inaugural
Bioinformatics & Cancerinformatics
Turning the Data Deluge into Meaningful Biological Knowledge
February 21-23, 2012
Moscone North Convention Center – San Francisco, CA
PDF Brochure Register TriConference.com/Bioinformatics-Cancerinformatics
Agenda at-a-Glance:
Tuesday, February 21
Grand Opening Refreshment Break in the Exhibit Hall with Poster Viewing
Sponsored by: Hologic DATA STORAGE, MANAGEMENT AND INTEGRATION STRATEGIES
KEYNOTE PRESENTATION: Data Liquidity: The Holy Grail at our Fingertips
Ken Buetow, Ph.D., former Director, Center for Biomedical Informatics and Information Technology, National Cancer Institute
PubChem as a Tool to Facilitate Drug Design
Jun (Luke) Huan, Ph.D., Associate Professor, Department of Electrical Engineering and Computer Science, University of Kansas
Oncology Pharmacogenomics Data Integration and Beyond: Right Information and Smart Information
Lihua Yu, Ph.D., Principal Scientist II, Oncology Innovative Medicine Unit, AstraZenenca PLC.
Luncheon Presentations (Opportunities Available)
Dessert in the Exhibit Hall with Poster Viewing
INTEGRATION OF DATA FOR BIOMARKER, CLINICAL AND PERSONALIZED MEDICINE STUDIES
Creating Informatics Tools and an Organizational Support Paradigm to Facilitate Bi-Directional Translational Research
Paul A. Harris, Ph.D., Director, Office of Research Informatics Operations; Associate Professor, Biomedical Informatics & Biomedical Engineering, Vanderbilt University
Secondary Use of Healthcare Data for the Study of Genomics and Pharmacology
Shawn Murphy, M.D., Ph.D., Associate Professor of Neurology, Research IT, Partners HealthCare
Clinical Research Informatics: Challenges and Opportunities in Translational Research
Carol Hill, Ph.D., Informatics Project Leader II, Clinical Data Integration, Duke Clinical Research Institute
Aggregating & Harmonizing Disparate Data Sources: The Key to Pattern Recognition
Gary Kennedy, Chairman & CEO, RemedyMD
Sponsored by: RemedyMD
Breaking the Mold: Whole Genome Sequencing as a Diagnostic Assay
Jill Hagenkord,MD Chief Medical Officer, Complete Genomics
Sponsored by: Complete Genomics
Breakout Discussions in the Exhibit Hall
Concurrent problem solving breakout discussions, open to all attendees, speakers, sponsors, and exhibitors, provide a forum for discussing key issues and meeting potential collaborators. Plan to take part and explore these topics in-depth. Please pick a topic of your choice, find your table and join in.
Transcription Factors
Moderator: Stuart Tugendreich, Product Management Director – IPA, Ingenuity Systems
* TF binding prediction vs. ChIP-Seq and other experimental approaches
* Post translational regulation of TFs and feedback loops
* TF cascades
* TFs as drug targets
Bridging the Gaps in Translational Informatics
Moderator: Jonathan Usuka, Ph.D., M.B.A., Director, Global Business Partnering, Celgene Corporation
* The $1000 Genome in the $100 Million Clinical Trial
* Do Novel Targets still matter? Pathway Analysis comes of age
* What do we know and when do we know it? Integrating biomarker and clinical data for
Go/No-Go decisions
* Three vital acronyms for 21st Century drug discovery: LIMS, ELNs and CROs
Causal vs Correlative Diagnostics and Biomarkers: Understanding the Difference
Moderators: Michael Liebman, Ph.D., Managing Director, Strategic Medicine, Inc. and
Sabrina Molinaro, Ph.D., Institute for Clinical Physiology, National Research Council, Italy
* Understanding the limitations of correlation and the opportunity for causality
* Analyzing and evaluating existing algorithms for risk and diagnosis
* The need to address biological complexity and process to the equation
Wednesday, February 22
DATA MODELING AND COMPUTATIONAL INTEGRATIVE TOOLS
Corrado Priami, Ph.D., President and CEO, The Microsoft Research – University of Trento Centre for Computational and Systems Biology (CoSBi)
Personalized Medicine: Moving from Correlation to Causality in Breast Cancer
Michael Liebman, Ph.D., Managing Director, Strategic Medicine, Inc.
Sabrina Molinaro, Ph.D., Institute for Clinical Physiology, National Research Council, Italy
Using Public Molecular Measurements to Drive Discovery of Biomarkers and Therapeutics
Rong Chen, Ph.D., Bioinformatics Specialist, Butte Lab, Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine
Prediction of Downstream Effects and Transcription Factor Activation of Breast Cancer Cell Lines Using IPA (Ingenuity Pathway Analysis)
Stuart Tugendreich, Ph.D., Product Management Director, Ingenuity Systems
Sponsored by: Ingenuity Systems
Transition to Plenary Keynote
Refreshment Break in the Exhibit Hall with Poster Viewing
Sponsored by: Hologic
GENOMICS AND INTEGRATING MULTIPLE -OMIC DATA TYPES
Clinical Grade Genomics: The Informatics Challenge
Peter J. Tonellato, Ph.D., Visiting Professor, Senior Research Scientist, Pathology, BIDMC & Center for Biomedical Informatics, Harvard Medical School
Integrative Network Biology Provides Novel Predictors of Human Disease
Rod Nibbe, Ph.D., Senior Scientist & Director of Product Development, NEO Proteomics, Inc.
Luncheon Presentation:
Using a Bioinformatics Approach to Gain a Better Understanding of the Unique Molecular Features of Non-squamous Cell Lung Cancer (NSCLC)
Kevin Bobofchak, Ph.D., Pathway Studio Product Manager, Elsevier
Sponsored by: Elsevier
Luncheon Presentation (Sponsorship Opportunity Available) or Lunch on Your Own
Ice Cream Refreshment Break in the Exhibit Hall with Poster Viewing
Refreshment Break & Poster Awards in the Exhibit Hall
GENE EXPRESSION & DATA ANALYSIS
Detection of Lung Cancer Molecular Subtypes by Gene Expression Arrays, Protein Immunohistochemistry and PCR from Paraffin Based Assays
David Neil Hayes, M.D., M.P.H., Assistant Professor, Clinical Research, Hematology/Oncology, University of North Carolina, Chapel Hill
Upstream Regulatory Pathways and Predicting Side Effects from Gene Expression Signatures
Avi Ma’ayan, Ph.D., Assistant Professor, Department of Pharmacology & Systems Therapeutics, Mount Sinai School of Medicine
Comparing Two Microarray Covariance Matrices Based on a Novel Conjugate Bayes Factor
James Zhou, Ph.D., Director, Statistical Operations, Clinical Development, Social & Scientific Systems, Inc.
Web Portal for Integrated Analysis of Radiation Responsive Cancer Gene Expression Profiles
Uma Shankavaram, Ph.D., Staff Scientist, National Cancer Institute & NIH
Thursday, February 23
TRANSLATING BIOMARKER DRIVEN CANCER TREATMENTS INTO PRACTICE
The Road to Personalized Medicine is Paved with Data and Information
John Quackenbush, Ph.D., Professor, Biostatistics and Computational Biology, Cancer Biology Center for Cancer, Dana-Farber Cancer Institute
Cancer Commons – A Rapid Learning Community for Cancer
Jay M. Tenenbaum, Ph.D., Founder and Chairman, Cancer Commons
Clinical Information Systems for Genome Directed Cancer Treatment
Mia Levy, M.D., Ph.D., Assistant Professor, Biomedical Informatics and Medicine, Vanderbilt University; Cancer Clinical Informatics Officer, Vanderbilt Ingram Cancer Center
Integrative Biology Approaches for Genome Interpretation in the Age of Personalized Medicine
Ilya Kupershmidt, Co-founder and Vice President, Products, NextBio
Sponsored by: NextBio
Coffee Break
How to Translate Next-Generation Sequencing Data into Clinically Useful Information
Fuad Gwadry, Bioinformatics Consultant, Sequenom Center for Molecular Medicine
Oral Chemotherapy Translation: Why a Web-Based Data Repository is Essential for Pharmacist Use of Oral Anticancer Treatments
Tibor van Rooij, Ph.D. Candidate, Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta
Skinomics – Part I
Miroslav Blumenberg, Ph.D., Associate Professor, Dermatology and Biochemistry, NYU Langone Medical Center
Luncheon Presentation (Sponsorship Opportunity Available) or Lunch on Your Own
TRANSLATING BIOMARKER DRIVEN CANCER TREATMENTS INTO PRACTICE
Skin-based Genomic Biomarkers for Disease Detection – Part II
William Wachsman, M.D., Ph.D. Associate Professor, Medicine, Hematology-Oncology, University of California, San Diego, School of Medicine
Pharmaceutical Information Solutions for Oncology
Jonathan Usuka, Ph.D., M.B.A., Director, Research & Development, Celgene Corporation
BIOINFORMATICS IN THE CLOUD
Bioinformatics in the Cloud: An Affordable Alternative
Giles Day, Co-founder and Managing Director, Distributed Bio, LLC
View speaker abstracts | Register
Sponsorship & Exhibit Opportunities are Available
Companies A-K: For details, contact Jon Stroup, 781-972-5483, jstroup@healthtech.com
Companies L-Z: For details, contact Joe Vacca, 781-972-5431, jvacca@healthtech.com
Group Discounts are Available
For details, contact David Cunningham at 781-972-5472, cunningham@healthtech.com
Ways to Register:
Web: www.triconference.com/mmtc/registration
Call: 781-972-5400
Bioinformatics & Cancerinformatics is part of the Informatics & Cancer Channel at the Molecular Med TRI-CON 2012 event.
TriConference.com/Bioinformatics-Cancerinformatics