Bioinformatics & Cancerinformatics

Cambridge Healthtech Institute’s Inaugural
Bioinformatics & Cancerinformatics
Turning the Data Deluge into Meaningful Biological Knowledge

February 21-23, 2012
Moscone North Convention Center – San Francisco, CA

PDF Brochure     Register     TriConference.com/Bioinformatics-Cancerinformatics


Agenda at-a-Glance:

Tuesday, February 21

Grand Opening Refreshment Break in the Exhibit Hall with Poster Viewing
Sponsored by: Hologic

DATA STORAGE, MANAGEMENT AND INTEGRATION STRATEGIES

KEYNOTE PRESENTATION: Data Liquidity: The Holy Grail at our Fingertips
Ken Buetow, Ph.D., former Director, Center for Biomedical Informatics and Information Technology, National Cancer Institute

PubChem as a Tool to Facilitate Drug Design
Jun (Luke) Huan, Ph.D., Associate Professor, Department of Electrical Engineering and Computer Science, University of Kansas

Oncology Pharmacogenomics Data Integration and Beyond: Right Information and Smart Information 
Lihua Yu, Ph.D., Principal Scientist II, Oncology Innovative Medicine Unit, AstraZenenca PLC.

Luncheon Presentations (Opportunities Available)

Dessert in the Exhibit Hall with Poster Viewing

INTEGRATION OF DATA FOR BIOMARKER, CLINICAL AND PERSONALIZED MEDICINE STUDIES

Creating Informatics Tools and an Organizational Support Paradigm to Facilitate Bi-Directional Translational Research
Paul A. Harris, Ph.D., Director, Office of Research Informatics Operations; Associate Professor, Biomedical Informatics & Biomedical Engineering, Vanderbilt University

Secondary Use of Healthcare Data for the Study of Genomics and Pharmacology
Shawn Murphy, M.D., Ph.D., Associate Professor of Neurology, Research IT, Partners HealthCare

Clinical Research Informatics: Challenges and Opportunities in Translational Research
Carol Hill, Ph.D., Informatics Project Leader II, Clinical Data Integration, Duke Clinical Research Institute

Aggregating & Harmonizing Disparate Data Sources: The Key to Pattern Recognition
Gary Kennedy, Chairman & CEO, RemedyMD
Sponsored by: RemedyMD


Breaking the Mold: Whole Genome Sequencing as a Diagnostic Assay
Jill Hagenkord,MD Chief Medical Officer, Complete Genomics
Sponsored by: Complete Genomics


Breakout Discussions in the Exhibit Hall

Concurrent problem solving breakout discussions, open to all attendees, speakers, sponsors, and exhibitors, provide a forum for discussing key issues and meeting potential collaborators. Plan to take part and explore these topics in-depth. Please pick a topic of your choice, find your table and join in.

Transcription Factors
Moderator: Stuart Tugendreich, Product Management Director – IPA, Ingenuity Systems

* TF binding prediction vs. ChIP-Seq and other experimental approaches
* Post translational regulation of TFs and feedback loops
* TF cascades
* TFs as drug targets

Bridging the Gaps in Translational Informatics
Moderator: Jonathan Usuka, Ph.D., M.B.A., Director, Global Business Partnering, Celgene Corporation

* The $1000 Genome in the $100 Million Clinical Trial
* Do Novel Targets still matter? Pathway Analysis comes of age
* What do we know and when do we know it? Integrating biomarker and clinical data for
   Go/No-Go decisions
* Three vital acronyms for 21st Century drug discovery: LIMS, ELNs and CROs

Causal vs Correlative Diagnostics and Biomarkers: Understanding the Difference
Moderators: Michael Liebman, Ph.D., Managing Director, Strategic Medicine, Inc. and
Sabrina Molinaro, Ph.D., Institute for Clinical Physiology, National Research Council, Italy

* Understanding the limitations of correlation and the opportunity for causality
* Analyzing and evaluating existing algorithms for risk and diagnosis
* The need to address biological complexity and process to the equation

Wednesday, February 22

DATA MODELING AND COMPUTATIONAL INTEGRATIVE TOOLS

Mastering Complexity of Biosystems without Math and Computing Background
Corrado Priami, Ph.D., President and CEO, The Microsoft Research – University of Trento Centre for Computational and Systems Biology (CoSBi)

Personalized Medicine: Moving from Correlation to Causality in Breast Cancer
Michael Liebman, Ph.D., Managing Director, Strategic Medicine, Inc.
Sabrina Molinaro, Ph.D., Institute for Clinical Physiology, National Research Council, Italy

Using Public Molecular Measurements to Drive Discovery of Biomarkers and Therapeutics
Rong Chen, Ph.D., Bioinformatics Specialist, Butte Lab, Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine

Prediction of Downstream Effects and Transcription Factor Activation of Breast Cancer Cell Lines Using IPA (Ingenuity Pathway Analysis)
Stuart Tugendreich, Ph.D., Product Management Director, Ingenuity Systems
Sponsored by: Ingenuity Systems


Transition to Plenary Keynote

Refreshment Break in the Exhibit Hall with Poster Viewing
Sponsored by: Hologic


GENOMICS AND INTEGRATING MULTIPLE -OMIC DATA TYPES

Clinical Grade Genomics: The Informatics Challenge
Peter J. Tonellato, Ph.D., Visiting Professor, Senior Research Scientist,  Pathology, BIDMC & Center for Biomedical Informatics, Harvard Medical School

Integrative Network Biology Provides Novel Predictors of Human Disease
Rod Nibbe, Ph.D., Senior Scientist & Director of Product Development, NEO Proteomics, Inc.

Luncheon Presentation:
Using a Bioinformatics Approach to Gain a Better Understanding of the Unique Molecular Features of Non-squamous Cell Lung Cancer (NSCLC)
Kevin Bobofchak, Ph.D., Pathway Studio Product Manager, Elsevier
Sponsored by: Elsevier


Luncheon Presentation (Sponsorship Opportunity Available) or Lunch on Your Own

Ice Cream Refreshment Break in the Exhibit Hall with Poster Viewing

Refreshment Break & Poster Awards in the Exhibit Hall

GENE EXPRESSION & DATA ANALYSIS

Detection of Lung Cancer Molecular Subtypes by Gene Expression Arrays, Protein Immunohistochemistry and PCR from Paraffin Based Assays
David Neil Hayes, M.D., M.P.H., Assistant Professor, Clinical Research, Hematology/Oncology, University of North Carolina, Chapel Hill

Upstream Regulatory Pathways and Predicting Side Effects from Gene Expression Signatures
Avi Ma’ayan, Ph.D., Assistant Professor, Department of Pharmacology & Systems Therapeutics, Mount Sinai School of Medicine

Comparing Two Microarray Covariance Matrices Based on a Novel Conjugate Bayes Factor
James Zhou, Ph.D., Director, Statistical Operations, Clinical Development, Social & Scientific Systems, Inc.

Web Portal for Integrated Analysis of Radiation Responsive Cancer Gene Expression Profiles
Uma Shankavaram, Ph.D., Staff Scientist, National Cancer Institute & NIH

Thursday, February 23

TRANSLATING BIOMARKER DRIVEN CANCER TREATMENTS INTO PRACTICE

The Road to Personalized Medicine is Paved with Data and Information
John Quackenbush, Ph.D., Professor, Biostatistics and Computational Biology, Cancer Biology Center for Cancer, Dana-Farber Cancer Institute

Cancer Commons – A Rapid Learning Community for Cancer
Jay M. Tenenbaum, Ph.D., Founder and Chairman, Cancer Commons

Clinical Information Systems for Genome Directed Cancer Treatment
Mia Levy, M.D., Ph.D., Assistant Professor, Biomedical Informatics and Medicine, Vanderbilt University; Cancer Clinical Informatics Officer, Vanderbilt Ingram Cancer Center

Integrative Biology Approaches for Genome Interpretation in the Age of Personalized Medicine
Ilya Kupershmidt, Co-founder and Vice President, Products, NextBio
Sponsored by: NextBio

Coffee Break

How to Translate Next-Generation Sequencing Data into Clinically Useful Information
Fuad Gwadry, Bioinformatics Consultant, Sequenom Center for Molecular Medicine

Oral Chemotherapy Translation: Why a Web-Based Data Repository is Essential for Pharmacist Use of Oral Anticancer Treatments
Tibor van Rooij, Ph.D. Candidate, Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta

Skinomics – Part I
Miroslav Blumenberg, Ph.D., Associate Professor, Dermatology and Biochemistry, NYU Langone Medical Center

Luncheon Presentation (Sponsorship Opportunity Available) or Lunch on Your Own

TRANSLATING BIOMARKER DRIVEN CANCER TREATMENTS INTO PRACTICE

Skin-based Genomic Biomarkers for Disease Detection – Part II
William Wachsman, M.D., Ph.D. Associate Professor, Medicine, Hematology-Oncology, University of California, San Diego, School of Medicine

Pharmaceutical Information Solutions for Oncology
Jonathan Usuka, Ph.D., M.B.A., Director, Research & Development, Celgene Corporation

BIOINFORMATICS IN THE CLOUD

Bioinformatics in the Cloud: An Affordable Alternative
Giles Day, Co-founder and Managing Director, Distributed Bio, LLC

View speaker abstracts | Register 


Sponsorship & Exhibit Opportunities are Available
Companies A-K: For details, contact Jon Stroup, 781-972-5483, jstroup@healthtech.com
Companies L-Z: For details, contact Joe Vacca, 781-972-5431, jvacca@healthtech.com

Group Discounts are Available
For details, contact David Cunningham at 781-972-5472,
cunningham@healthtech.com

Ways to Register:
Web:
www.triconference.com/mmtc/registration
Call:
781-972-5400


Bioinformatics & Cancerinformatics is part of the Informatics & Cancer Channel at the Molecular Med TRI-CON 2012 event.


TriConference.com/Bioinformatics-Cancerinformatics