KnowItAll 3.1 Offers Advances in ADME | Tox Prediction
PHILADELPHIA, PA, February 12, 2004 – Bio-Rad Laboratories, Inc. (AMEX: BIO and BIO.B) announced today the release of the KnowItAll® Informatics System version 3.1 and further advances in ADME/Tox prediction. Below are some highlights and additions in the new release:
- Bio-Rad’s ProfileIt™ is a new application that enables scientists to generate a comprehensive ADME/Tox profile that can be used to assess a compound’s potential for advancement in pharmaceutical R&D. The program allows the user to view the results of all prediction models in the KnowItAll software, such as Blood Brain Barrier Permeability, log D, log P, Mutagenicty, Plasma Protein Binding in a consolidated report format for any compound.
- KnowItAll 3.1 also offers a Human Intestinal Absorption prediction model from ChemSilico LLC to help researchers determine whether not a drug candidate has a suitable oral absorption rate.
- With this release, all editions of the KnowItAll Informatics System, including Bio-Rad’s solutions for Spectroscopy and Cheminformatics, offer improved datamining capabilities, including the ability to color code and assign weighting factors to values based on pre-defined rules for each property.
Dr. Michelle D’ Souza, Bio-Rad’s Medicinal Chemistry Software Product Manager commented, “These latest enhancements to our award-winning ADME/Tox prediction suite highlight Bio-Rad’s commitment to developing market-leading applications for the drug discovery community.”
Bio-Rad’s Informatics Division (www.informatics.bio-rad.com) specializes in state-of-the-art software and database solutions for the pharmaceutical, biotech, and chemical industries. Bio-Rad is the leading publisher of fully verified spectral databases, cheminformatics, spectroscopy software and decision support systems for drug discovery. The company’s award-winning KnowItAll Informatics System offers a fully integrated environment with flexible, expandable software and database solutions for spectroscopy (MS, NMR, IR, Raman, spectral data management), cheminformatics and ADME/Tox prediction.
Bio-Rad Laboratories, Inc. (www.bio-rad.com) is a multinational manufacturer and distributor of life science research, clinical diagnostics and informatics products. It is based in Hercules, California, and serves more than 70,000 research and industry customers worldwide through a network of more than 30 wholly owned subsidiary offices.
Various statements made within this press release may constitute “forward-looking statements” for purposes of the Securities and Exchange Commission’s “safe harbor” provisions under the Private Securities Litigation Reform Act of 1995 and Rule 3b-6 under the Securities Exchange Act of 1934. The forward-looking statements contained herein involve risks and uncertainties that could cause results to differ materially from the Company’s expectations.
For more information, contact:
Name: Deborah Kernan
Phone: +1 215 349 7366
E-mail: [email]deborah_kernan@bio-rad.com[/email]
For additional information on Bio-Rad Laboratories, Informatics Division, visit www.informatics.bio-rad.com or call 1-888-5-BIO-RAD in the U.S. or in Europe, call +44 (0) 20 8328 2555 or free phone 00800-78945000.
