National Oceanic and Atmospheric Administration Licenses the Rosetta Resolver Gene Expression Data Analysis System
SEATTLE & WASHINGTON–(BUSINESS WIRE)–Aug. 1, 2006–Rosetta Biosoftware announced today that the National Oceanic and Atmospheric Administration (NOAA) has purchased a license for its Rosetta Resolver(R) system to conduct research on the toxicogenomic response of animal models and protected marine species to marine biotoxins. The Resolver system will be used by NOAA’s Marine Biotoxins Program at the Center for Coastal Environmental Health and Biomolecular Research (CCEHBR) in Charleston, South Carolina. As part of its mission, the Center carries out research and provides analytical services to evaluate the health effects of algal toxins on marine animals and humans.
“The Resolver system will be a key element of our microarray facility at CCEHBR. It will help us characterize the global transcriptional response of human cell lines and other models to marine neurotoxins,” said Jimmy Ryan, Molecular Biologist, who is leading this research element within NOAA’s Marine Biotoxins Program. “These efforts at CCEHBR are targeted towards alleviating the adverse effects that marine biotoxins have on people and the environment through functional genomic and toxicogenomic studies.”
The Marine Biotoxins Program at CCEHBR targets its research at harmful algal blooms (HABs) and the potent toxins produced by them. HABs are proliferations of microscopic algae that occur on all coasts of the US. Potent neurotoxins produced by HABs cause mass mortalities of marine life, including protected marine mammals, and can accumulate in shellfish, causing closure of shellfishing industries and human health concerns.
“The Rosetta Resolver system is a versatile and reliable solution to conduct toxicogenomics studies, determine biological mechanisms, and identify biomarkers,” said Yelena Shevelenko, vice president and general manager of Rosetta Biosoftware. “We are excited to see the functionality of the Resolver system expand to the important area of marine biotoxin research, conducted by this comprehensive national program.”
The Rosetta Resolver system is developed and supported by Rosetta Biosoftware and is distributed exclusively by Agilent Technologies.
For more information about CCEHBR and the Marine Biotoxins Program, visit www.chbr.noaa.gov. For more information about NOAA visit www.noaa.gov.
About the Rosetta Resolver System
The Rosetta Resolver system is a high-capacity data storage, retrieval, and analysis solution for gene expression data. The system is ideal for life science research organizations that need to assess compound specificity or toxicity, identify new genes or therapeutic targets or compare and analyze large databases of expression profiles. The Rosetta Resolver system combines flexibility and ease of use with high-performance algorithms to produce a comprehensive solution for rapid analysis of gene expression data. The Rosetta Resolver system can accept and analyze data from a wide variety of expression profiling formats, including Agilent DNA microarrays, and applies Rosetta Biosoftware’s proprietary error models to yield quality statistics for every gene expression measurement within the system. These statistics are automatically leveraged by Rosetta Resolver system analysis tools for optimal results.
Life science research organizations that have licensed the Rosetta Resolver system include many of the top pharmaceutical companies in the world, such as Sanofi-Aventis Pharmaceuticals, Bristol-Myers Squibb, GlaxoSmithKline and Merck & Co., Inc., as well as premier academic institutions such as the Harvard University Center for Genomics Research and the California Institute of Technology. Additional information about the Rosetta Resolver system can be found on the Rosetta Biosoftware Web site at www.rosettabio.com .
About Rosetta Biosoftware
Rosetta Biosoftware is a leading provider of informatics solutions for life science research. Its enterprise software solutions, including the Rosetta Resolver and Rosetta Elucidator systems, empower life scientists with advanced, scalable, and easy-to-use analysis platforms that accelerate discovery research. Rosetta Biosoftware is a business unit of Rosetta Inpharmatics LLC, a wholly owned subsidiary of Merck & Co., Inc. (NYSE:MRK). More information about Rosetta Biosoftware is available at www.rosettabio.com .
Rosetta Resolver and Elucidator are U.S. registered trademarks of Rosetta Inpharmatics LLC.
