Scientist, Next Generation Sequencing Core (NCI)
PROGRAM DESCRIPTION
The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and provides dedicated support to NCI's intramural Center for Cancer Research (CCR). The dedicated units provide next generation sequencing, electron microscopy, protein characterization, protein expression, optical microscopy and genetics. These research efforts are an integral part of CCR at the Frederick National Laboratory for Cancer Research (FNLCR). CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise.
KEY ROLES/RESPONSIBILITIES
The Sequencing Facility is a high throughput laboratory providing cutting edge next generation technologies to the National Cancer Institute.
The Scientist I will be responsible for:
– Assisting with Next Generation (NGS) Sequencing for the core facility. Current platforms include the Illumina HiSeq, NextSeq, MiSeq, PacBio, and additional platforms in the future. All projects are of a highly specialized nature and require technical proficiency, problem solving skills and good judgment
– Work with SF Research & Development group, Director, group leaders and informatics staff to develop, implement, and perform laboratory processes in support of the SF operations, especially for development in the field of long read technology
– Assist in the identification, research, optimization and implementation of new processes or technologies that serve to introduce new applications, or improve data quality or efficiency of production pipelines, especially with a focus on long read sequencing applications
– Coordinate with SF, quality management and informatics personnel to implement updates to equipment, chemistry, and processes
– Remain current with new applications and technologies associated with NGS sample preparation, library construction, sample enrichment and target capture
Requirements:
KEY ROLES/RESPONSIBILITIES
The Sequencing Facility is a high throughput laboratory providing cutting edge next generation technologies to the National Cancer Institute.
The Scientist I will be responsible for:
– Assisting with Next Generation (NGS) Sequencing for the core facility. Current platforms include the Illumina HiSeq, NextSeq, MiSeq, PacBio, and additional platforms in the future. All projects are of a highly specialized nature and require technical proficiency, problem solving skills and good judgment
– Work with SF Research & Development group, Director, group leaders and informatics staff to develop, implement, and perform laboratory processes in support of the SF operations, especially for development in the field of long read technology
– Assist in the identification, research, optimization and implementation of new processes or technologies that serve to introduce new applications, or improve data quality or efficiency of production pipelines, especially with a focus on long read sequencing applications
– Coordinate with SF, quality management and informatics personnel to implement updates to equipment, chemistry, and processes
– Remain current with new applications and technologies associated with NGS sample preparation, library construction, sample enrichment and target capture
Qualifications:
BASIC QUALIFICATIONS
To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:
– Possession of a Doctoral degree from an accredited college or university according to the Council for Higher Education Accreditation. (Additional qualifying experience may be substituted for the required education). Foreign degrees must be evaluated for U.S. equivalency.
– No work experience beyond the doctorate is required for appointment at this level; however, some candidates may have had one or more years of postdoctoral research and training
– Demonstrated experience in molecular biology or genetics/genomics, isolation, and manipulation of DNA and RNA, gel electrophoresis, high throughput platforms, applications, and technology
– Demonstrated ability for independent design and performance of experiments, capable of trouble shooting assays or production problems, and ability to develop/optimize new assays or production methods under the direction of a lab supervisor or scientist
– Proficiency in MS Excel, Word, and PowerPoint
– Must be able to obtain and maintain a security clearance
PREFERRED QUALIFICATIONS
– Experience working within a core/service facility
– Experience with Illumina (Solexa), Pacbio, or other NGS sequencing platforms, generation of libraries, sequencer operation, and maintenance
– Experience with next gen sequencing development, troubleshooting, analysis, and laboratory automation
– Familiarity with usage of a LIMS
– Good oral and written communication skills, and proficient organizational and time management capabilities
Leidos Overview:
Leidos is a global science and technology solutions leader working to solve the world's toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company's 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS&GS). For more information, visit www.Leidos.com. The company's diverse employees support vital missions for government and commercial customers. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. Leidos will consider qualified applicants with criminal histories for employment in accordance with relevant Laws. Leidos is an equal opportunity employer/disability/vet.
