Symyx Isentris 3.0 Gives Scientists New Power to Improve R&D

SANTA CLARA, Calif.–(BUSINESS WIRE)–Symyx Technologies, Inc. (Nasdaq:SMMX) is pleased to announce enhancements to the MDL Isentris informatics system (henceforth known as Symyx Isentris), giving research organizations improved ability to speed R&D experimentation, reduce costs and improve productivity. Symyx Isentris 3.0 bridges internal and external information in a single search, alerting researchers to relevant data and integrating leading scientific tools on the desktop.

By delivering appropriate information into workflows, Symyx Isentris 3.0 ensures that researchers make informed decisions, said Timothy Campbell, President of Symyx Software. As researchers browse data, Isentris performs simultaneous searches in the background, flagging important toxicity data, biological activity, in-house and commercial compound availability — instantly pushing relevant information to researchers. This critical information would otherwise require multiple specific searches to find or possibly be missed.

Available today, the new capabilities in Isentris 3.0 offer significant enhancements over its predecessor, ISIS. Symyx Isentris enables scientist-empowered access, personalized data views, flagging of relevant data and other features that dramatically improve the efficiency and productivity of scientific research and development. With easy deployment and many out-of-the-box productivity features, Symyx Isentris integrates applications, data and business rules.

The vision and strategy underlying Isentris grew out of extensive discussions with our customers, said Dr. Trevor Heritage, Senior Vice President of Science, Symyx Software. By listening closely, we gained an intimate understanding of the challenges scientists face in accessing, processing, managing and analyzing data. The solution that has emerged is the most powerful system for knowledge registration, information delivery and decision support available today.

With Isentris 3.0, researchers can quickly create forms to retrieve the precise chemical and biological data they want, without relying on IT assistance. Researchers can save sophisticated searches and use the same forms to generate comprehensive reports for sharing with colleagues. Synthetic chemists can formulate reaction plans using a powerful reaction planning tool while leveraging access to the worlds largest set of reaction databases — over 17 million reactions — including access to CrossFire Beilstein, other Symyx reaction data sources and in-house reaction data.

Once researchers identify the exact information they need, Isentris provides power to manipulate data and presentation in Microsoft Excel spreadsheets, visualize test results using visual analytics software like TIBCO Spotfire DecisionSite, enrich data using Web services and industry-standard calculators and apply nomenclature software, NMR and molecular property predictors from ACD/Labs.

Symyx Isentris leverages technologies and infrastructure that are standard in life sciences and chemicals R&D labs to deliver rapid application development, high performance and scalability to meet the needs of growing global R&D organizations. Isentris provides opportunities to improve productivity through better data management, lowered cost of ownership, faster workflow processes and easier information access and reporting. For more information, including short videos of unique Isentris advantages, or to register for free Webinars, visit www.mdl.com.

About Symyx

Symyx Technologies, Inc. is the R&D execution partner to the life sciences, chemicals, energy, consumer products and electronics industries. Symyx provides electronic lab notebook and scientific decision-support software, automated lab systems (workflows) and collaborative research services to improve R&D productivity. In October 2007, Symyx acquired MDL Information Systems, Inc., a leading provider of innovative informatics software, databases and services that accelerate successful scientific R&D by improving the speed and quality of scientists decision making. Information about Symyx, including reports and other information filed by Symyx with the Securities and Exchange Commission, is available at www.symyx.com.

Symyx and Isentris are registered trademarks of Symyx Technologies, Inc. Microsoft and Excel are registered trademarks of the Microsoft Corporation in the United States and other countries. TIBCO, Spotfire and DecisionSite are trademarks or registered trademarks of TIBCO Software Inc. in the United States and/or other countries. All rights reserved. All other trademarks mentioned in this document are the property of their respective owners.