Thermo’s New QuickQuan Software Provides Fast, Automated, LC-MS/MS Quantification for High-Throughput Drug Discovery
Thermo Electron Corporation introduces its new QuickQuan software for automating high-throughput LC-MS/MS assays in early drug discovery. The combination of QuickQuan’s rapid compound tune and optimization time with Thermo’s Finnigan TSQ Quantum triple quadrupole mass spectrometer is key to automatically assessing new chemical entities (NCEs) in early drug development assays such as metabolic stability. The innovative QuickQuan software will be showcased at Thermo’s booth ##105-204 in Hall B1, at Analytica, April 25-28, at the New Munich Trade Fair Centre in Munich, Germany.
QuickQuan delivers rapid LC-MS/MS optimization through use of an automated on-line infusion mode and valve switching design. This allows for precise auto-tuning with high sensitivity that, consequently, maximizes successful automated quantification of chemically diverse compounds. All analytical information is stored either in Microsoft Access® or Oracle® databases, which facilitates rapid data exchange across global networks.
“Pharmaceutical researchers tell us that manual LC-MS/MS method development can be time consuming for analysts considering, for example, that it may take as long as five to ten hours to process 30 compounds” says Iain Mylchreest, vice president and general manager of Life Sciences Mass Spectrometry for Thermo. “Thermo’s QuickQuan solution minimizes manual intervention and significantly increases productivity in demanding, high-throughput applications such as CACO-2 assays by as much as 75%.”
For more information about Thermo’s new QuickQuan software, visit booth #105-204 in Hall B1 at Analytica 2006. Alternatively, please e-mail analyze@thermo.com or visit www.thermo.com/ms
About Chromatography and Mass Spectrometry
A market leader in ion trap, hybrid, magnetic sector mass spectrometers, and hyphenated multi-instrument combinations of these products, Thermo’s integrated solutions include state-of-the-art instrument systems, advanced software and HPLC column technology with a wide range of innovative phases and hardware designs – tailored to meet the rigorous demands of lab professionals in applications such as proteomics, drug discovery, environmental analysis and analytical quantification. For more information, visit www.thermo.com/ms
About Thermo Electron Corporation
Thermo Electron Corporation is the world leader in analytical instruments. Our instrument solutions enable our customers to make the world a healthier, cleaner and safer place. Thermo’s Life and Laboratory Sciences segment provides analytical instruments, scientific equipment, services and software solutions for life science, drug discovery, clinical, environmental and industrial laboratories. Thermo’s Measurement and Control segment is dedicated to providing analytical instruments used in a variety of manufacturing processes and in-the-field applications, including those associated with safety and homeland security.
