Tripos Announces Benchware Discovery 360; New Software Boosts Discovery Productivity; Scientists Now Able to Access and Analyze Enterprise Chemical and Biological Data from a Single Integrated Desktop Discovery Environment

BOSTON–(BUSINESS WIRE)–Aug. 9, 2006–Tripos, Inc. (Nasdaq:TRPS), a leading provider of drug discovery informatics products and chemistry research, today announced Benchware(R) Discovery 360, a new software solution enabling discovery scientists to easily access and analyze enterprisewide chemical and biological research data from within a single integrated desktop discovery environment. Benchware Discovery 360 was unveiled at the Drug Discovery Technology(R) & Development World Congress in Boston, and becomes the newest member of the Benchware family of applications designed especially for laboratory scientists, including discovery chemists and biologists.

Benchware Discovery 360 provides scientists and research managers with a single point of entry from which they can access, analyze and share data from disparate enterprise repositories of biological and chemical data. In addition, Benchware Discovery 360 integrates seamlessly with applications from other vendors, providing researchers access to their favorite analysis and productivity tools. These capabilities enable life science organizations to gain better insight into their drug discovery projects, improve scientific collaboration, and allow discovery teams to fully realize the value in the data they are generating.

Benchware Discovery 360 is based on the award-winning SMART-IDEA(TM) informatics system that Tripos originally built in collaboration with Bristol-Myers Squibb Co., and which is also forming the basis of a next-generation discovery IT solution, announced earlier this year, for Wyeth Pharmaceuticals. The Bristol-Myers Squibb implementation is currently deployed to 1,000 users throughout the U.S. and Canada. It allows scientists and team leaders to access and analyze essential project information on demand, resulting in improved decision-making and better overall discovery performance.

“Many of today’s discovery data warehouse solutions require chemists and biologists to become information technology specialists instead of more informed and agile discovery scientists,” said Bryan Koontz, senior vice president and general manager of Discovery Informatics for Tripos. “Instead of wasting valuable time formulating complicated queries or being forced to become Microsoft Excel experts, project teams using Benchware Discovery 360 can now quickly find, analyze and act on the research data they need, no matter where it exists inside their company. The result is a substantial improvement to a company’s overall discovery performance.”

Interested parties may learn more about Benchware Discovery 360 at the Tripos exhibition booth No. 733 as well as at a Tripos-led technology workshop on Aug. 9 at 2:50 p.m. More information on the Benchware Discovery 360 offering can be found at http://www.tripos.com/discovery360 .

About Benchware

The Benchware line of products from Tripos was first unveiled during last year’s Drug Discovery Technology & Development World Congress in Boston. Other products in the Tripos Benchware portfolio include Benchware HTS DataMiner, for the analysis and visualization of multidimensional high-throughput screening data; Benchware 3D Explorer, for 3-D molecular visualization and communication; and Benchware Notebook, an enterprise-class electronic laboratory notebook.

About Tripos, Inc.

Tripos (Nasdaq:TRPS) combines leading-edge technology and innovative science to deliver consistently superior chemistry-research products and services for the biotechnology, pharmaceutical and other life science industries. Within Tripos’ Discovery Informatics (DI) business, the company provides software products and consulting services to develop, manage, analyze and share critical drug discovery information. Within Tripos’ Discovery Research (DR) business, Tripos’ medicinal chemists and research scientists partner directly with clients in their research initiatives, leveraging state-of-the-art information technologies and research facilities. Headquartered in St. Louis, Mo., Tripos spans the world with global research operations and an international client base. Further information on Tripos can be found at http://www.tripos.com .

Tripos and the Tripos logo are registered trademarks of Tripos, Inc. and/or its affiliates in the United States and certain other countries. All other trademarks mentioned in this document are the property of their respective owners.