Analysis of cannabidiol, delta-9-tetrahydrocannabinol, and their acids in CBD/hemp oil products

In this 2020 paper published in Medical Cannabis and Cannabinoids, ElSohly et al. present the results from an effort to demonstrate the use of a relatively basic gas chromatography–mass spectrometry (GC-MS) method for accurately measuring the cannabidiol, tetrahydrocannabinol, cannabidiolic acid, and tetrahydrocannabinol acid content of CBD oil and hemp oil products. Noting the problems with inaccurate labels and the proliferation of CBD products suddenly for sale, the authors emphasize the importance of a precise and reproducible method for ensuring those products’ cannabinoid and acid precursor concentration claims are accurate. From their results, they conclude their validated method achieves that goal.

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