Chemometric analysis of cannabinoids: Chemotaxonomy and domestication syndrome

In this 2018 paper published in Scientific Reports, Mudge et al. of the University of British Columbia attempt to demonstrate how a growing loss of biodiversity is occurring across strains of Cannabis due to cultivation practices. The authors introduce current research on the “understanding of metabolite commonality and diversity within plant species” and hypothesize that simply measuring cannabinoid potency (Δ9-tetrahydrocannabinol or THC) and cannabidiol (CBD) content is not sufficient in painting a proper picture of cannabinoid composition and the resulting impact of breeding programs. The authors then get into the results of their analytical research, discuss their findings, and conclude that, at least in Canada, ” evaluating single metabolite classes [of available Cannabis strains] does not provide sufficient information to understand the phytochemical diversity available.”

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