Eleven quick tips for architecting biomedical informatics workflows with cloud computing

In this educational journal article published in PLoS Computational Biology, Cole and Moore of the University of Pennsylvania's Institute for Biomedical Informatics offer 11 tips for health informatics researchers and practitioners to embrace in improving reproducibility, knowledge sharing, and costs: adopt cloud computing. The authors compare more traditional "in-house enterprise compute systems such as high-performance computing (HPC) clusters" located in academic institutions with more agile cloud computing installations, showing various ways researchers can benefit from building biomedical informatics workflows on the cloud. After sharing their tips, they conclude that "[c]loud computing offers the potential to completely transform biomedical computing by fundamentally shifting computing from local hardware and software to on-demand use of virtualized infrastructure in an environment which is accessible to all other researchers."

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