In this educational journal article published in PLoS Computational Biology, Cole and Moore of the University of Pennsylvania's Institute for Biomedical Informatics offer 11 tips for health informatics researchers and practitioners to embrace in improving reproducibility, knowledge sharing, and costs: adopt cloud computing. The authors compare more traditional "in-house enterprise compute systems such as high-performance computing (HPC) clusters" located in academic institutions with more agile cloud computing installations, showing various ways researchers can benefit from building biomedical informatics workflows on the cloud. After sharing their tips, they conclude that "[c]loud computing offers the potential to completely transform biomedical computing by fundamentally shifting computing from local hardware and software to on-demand use of virtualized infrastructure in an environment which is accessible to all other researchers."
Jupyter Notebook, an open-source interactive web application for the data science and scientific computing community (and with some of the features of an electronic laboratory notebook), has been publicly available since 2015, helping scientists make computational records of their research. In this 2018 tutorial article by Friedrich-Schiller-Universität Jena's Phillipp Sprengholz, the installation procedures and features are presented, particularly in the context of aiding psychological researchers with their efforts in making research more reproducible and shareable.
This recorded Lab Informatics Tutorial series is designed as a management level view of laboratory systems and is appropriate for anyone planning, reviewing, or approving the acquisition of laboratory informatics. A background in science is not necessary to follow the presented material. Its purpose is to provide you with an understanding of how these technologies (Laboratory Information Management Systems, Electronic Laboratory Notebooks, Scientific Data Management Systems, Laboratory Execution Systems, Instrument Data Systems, and supporting technologies ) can be used to support/improve your labs operations, and the considerations that need to be taken into account before they are purchased.
In today’s global economy, mergers and acquisitions have become a dominant strategy to improve profitability, maintain competitive edge, and expand services and reach. This practice is common in several industries such as pharmaceutical, biotech, food and beverage, oil and gas, and others. While corporate mergers certainly can provide several benefits for the organizations involved, they can also present significant challenges, not the least of which is harmonization and optimization of the laboratory environment. This often leads to the need to the need for integrating multiple LIMS apps to support a global enterprise.
Any entity that stores biological samples can be called a Biobank. However, the term ‘Biobank’ is most commonly used for entities that store biological specimens on a large scale to provide them as a service for internal or external entities like researchers. Biobanks have to offer unbiased and high-quality samples using well-designed and documented procedures. This ensures a biological specimen is kept in a controlled environment and guarantees the ethical aspect of sample collection.
FDA Guidance for Good Clinical Practice (GCP) is an international quality standard defined by the International Council for Harmonization (ICH) that governs ethical and scientific considerations for designing, conducting, recording and reporting trials involving human subjects. Compliance with FDA Guidance for GCP in clinical trials helps to assure that the rights, well-being and safety of trial participants are protected and that the data generated in the trial is credible.