Bioinformatics workflow for clinical whole genome sequencing at Partners HealthCare Personalized Medicine
Genomic data is increasingly used to provide better, more focused clinical care. Or course, its associated datasets can be large, and it can take significant processing power to utilize and manage effectively. In this 2016 paper published in Journal of Personalized Medicine, Tsai et al. of Partners Healthcare describe their "bioinformatics strategy to efficiently process and deliver genomic data to geneticists for clinical interpretation." They conclude that with more research comes improved workflows and "filtrations that include larger portions of the non-coding regions as they start to have utility in the clinical setting, ultimately enabling the full utility of complete genome sequencing."
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