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John Wayne Kappler (born December 22, 1943, in Baltimore, Maryland) is a professor in the Department of Integrated Immunology at National Jewish Health.[2] His principal research is in T cell biology, a subject he collaborates on with his wife Philippa Marrack.[3] In 1983 they discovered the T cell receptor, together with Ellis Reinherz and James Allison.

John Kappler
Born(1943-12-22)December 22, 1943
Alma mater
Known fordiscovery of T cell receptor
AwardsWolf Prize in Medicine, 2015
Scientific career
WebsiteKM lab website



  1. ^ "John W. Kappler".
  2. ^ "John Kappler, PhD". Archived from the original on May 17, 2008. Retrieved November 2, 2008.
  3. ^ Rennie, J. (1992) Profile: Philippa Marrack and John Kappler – Keeping It In the Family, Scientific American 267(2), 43-44.