Dacemazine
Identifiers
  • 2-dimethylamino-1-phenothiazin-10-ylethanone
CAS Number
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H16N2OS
Molar mass284.376 g/mol g·mol−1
3D model (JSmol)
  • CN(C)CC(=O)N1C2=CC=CC=C2SC3=CC=CC=C31

Dacemazine (INN, also known as Ahistan and Histantine)[1] is a phenothiazine derivative which acts as an histamine antagonist at the H1 subtype. First described in 1951, it was never marketed as a drug on its own, although a combination of dacemazine and di-tert-butylnaphthalenesulfonate was sold as an antispasmodic and antitussive under the trade name Codopectyl.[1]

References

  1. ^ a b David J. Triggle (1996). Dictionary of Pharmacological Agents. Vol. 1. Boca Raton: Chapman & Hall/CRC. pp. p. 711. ISBN 0-412-46630-9. {{cite book}}: |pages= has extra text (help); Unknown parameter |coauthors= ignored (|author= suggested) (help) Retrieved on August 2, 2008 through Google Book Search.