Laboratory Informatics Weekly Update – Volume 14, Issue 1

January 06, 2016      Laboratory Informatics Weekly Update  Volume 14, Issue 1   In This Issue  Webcast Focus JANUARY 20, 2016, 2:00pm EST: Get the Most from your Waters Empower™ 3 Upgrade Is there an upgrade to Waters Empower 3 in your near future? Join this webinar as we describe some of the most important new features of Empower 3 and outline a process that will ensure that your laboratory organization will “Get the Most from your Waters Empower 3 Upgrade”.  Event Focus JANUARY 23, 2016: SLAS2016 SLAS2016 takes place January 23-27 in San Diego, California. Programmed by scientists and engineers for…

Case Study: RTI Laboratories

Nationally recognized laboratory slashes operating costs and boosts productivity over 20% with Khemia's Omega 11

Laboratory Informatics Weekly Update – Volume 13, Issue 49

December 30, 2015      Laboratory Informatics Weekly Update  Volume 13, Issue 49   In This Issue  Webcast Focus Get the Most from your Waters Empower™ 3 Upgrade Is there an upgrade to Waters Empower 3 in your near future? Join this webinar as we describe some of the most important new features of Empower 3 and outline a process that will ensure that your laboratory organization will “Get the Most from your Waters Empower 3 Upgrade”.  Event Focus JANUARY 23, 2016: SLAS2016 SLAS2016 takes place January 23-27 in San Diego, California. Programmed by scientists and engineers for peers interested in leveraging the…

SeqWare Query Engine: Storing and searching sequence data in the cloud

In 2010, O'Connor et al. published a paper on their experience developing and implementing a cloud-based query engine that can support thousands of genome datasets. Still actively developed as of 2015, the SeqWare Query Engine "can load and query variants (SNVs, indels, translocations, etc) with a rich level of annotations including coverage and functional consequences." The research team concluded in their paper that the software was then "capable of supporting large scale genome sequencing research projects involving hundreds to thousands of genomes as well as future large scale clinical deployments utilizing advanced sequencer technology that will soon involve tens to hundreds of thousands of genomes."

SaDA: From sampling to data analysis—An extensible open source infrastructure for rapid, robust and automated management and analysis of modern ecological high-throughput microarray data

In 2015, Singh et al. published their notes and reflections on developing SaDA, designed "for storing, retrieving and analyzing data originated from microorganism monitoring experiments." The group developed the software after discovering a lack of free, open-source software for microarray data management and analysis. The group concluded that "the platform has the potential to become an appropriate tool for a wide range of users focused not only in water based environmental research but also in other studies aimed at exploring and analyzing complex ecological habitats."

Launching genomics into the cloud: Deployment of Mercury, a next generation sequence analysis pipeline

Seeking to overcome some of the challenges of massively parallel DNA sequencing, Reid et al. developed the Mercury analysis pipeline and deployed it on Amazon Web Services. Publishing their results in 2014 in BMC Bioinformatics, the group demonstrated the success of "a powerful combination of a robust and fully validated software pipeline and a scalable computational resource that, to date, we have applied to more than 10,000 whole genome and whole exome samples."

Best Blogs of 2015

Twice a week, we sit down and ask ourselves: "What do you want to hear about?" Our goal is to select blog topics that answer your questions. Here is a post listing some of the best blogs we wrote in 2015.

Benefits of the community for partners of open source vendors

Appearing in the magazine Open Source Business Resource (today called Technology Innovation Management Review) in 2011, this non-journal article by Sandro Groganz describes how "[o]pen source vendors can benefit from business ecosystems that form around their products," using open-source OXID eShop and its vendor OXID eSales as a representative example. Groganz concludes that "an open source community is not a state but a process," one that "creates a foundation for long-term growth and sustainability" when appropriately embraced.

Laboratory Informatics Weekly Update – Volume 13, Issue 48

December 17, 2015      Laboratory Informatics Weekly Update  Volume 13, Issue 48   In This Issue  Event Focus JANUARY 23, 2016: SLAS2016 SLAS2016 takes place January 23-27 in San Diego, California. Programmed by scientists and engineers for peers interested in leveraging the latest in scientific technology. Best-in-class information, innovation and inspiration at the intersection of science and technology. See www.slas2016.org for details and to register. JANUARY 25, 2016: 11th Laboratory Informatics Summit Timelines are tighter than ever before and informatics teams must constantly adapt to the changing demands of research science. Furthermore, periodic updates to your systems calls for a comprehensive implementation…

adLIMS: A customized open source software that allows bridging clinical and basic molecular research studies

The San Raffaele Telethon Institute for Gene Therapy wanted a new LIMS to manage the data coming from their PCR techniques and next generation sequencing (NGS) methods. Not finding something suitable, the group developed its own LIMS, adLIMS. This 2015 research paper by Calabria et al., published in BMC Bioinformatics, covers the academic aspects of the information collection and development process.

MendeLIMS: A web-based laboratory information management system for clinical genome sequencing

This 2014 research published in BMC Bioinformatics sees Grimes and Ji presenting their "highly configurable and extensible" web-based laboratory information management system (LIMS) for next generation DNA sequencing, MendeLIMS. The group concludes that the software is "an invaluable tool for the management of our clinical sequencing studies," primarily due to its ability to reduce sample tracking errors and give "a comprehensive view of data being sequenced."

Laboratory Informatics Weekly Update – Volume 13, Issue 47

December 09, 2015      Laboratory Informatics Weekly Update  Volume 13, Issue 47   In This Issue  Event Focus JANUARY 23, 2016: SLAS2016 SLAS2016 takes place January 23-27 in San Diego, California. Programmed by scientists and engineers for peers interested in leveraging the latest in scientific technology. Best-in-class information, innovation and inspiration at the intersection of science and technology. See www.slas2016.org for details and to register. JANUARY 25, 2016: 11th Laboratory Informatics Summit Timelines are tighter than ever before and informatics teams must constantly adapt to the changing demands of research science. Furthermore, periodic updates to your systems calls for a comprehensive implementation…