A sustainable approach for the reliable and simultaneous determination of terpenoids and cannabinoids in hemp inflorescences by vacuum-assisted headspace solid-phase microextraction

In this 2022 journal article published in Advances in Sample Preparation, Capetti et al. of Università di Torino investigate the advantages and disadvantages that vacuum-assisted headspace solid-phase microextraction (Vac-HSSPME) may lend to the process of Cannabis inflorescence preparation and subsequent testing, by gas chromatography–mass spectrometry (GC-MS), in order to accurately characterize both terpenoid and cannabinoid profiles. After providing an introduction on the topic, the authors describe the materials and methods used, as well as the results of their study. They conclude that "compared to standard HSSPME, vacuum conditions in the headspace ensure the fast recovery of cannabinoid markers at considerably lower sampling temperature (i.e., 90°C) that do not discriminate the most volatile fraction nor cause the formation of artifacts when the sampling time is minimized." They add that, in combination with GC-MS, Vac-HSSPME can prove to be "fast, totally automatable, and solvent-free," representing a more green analytical approach to Cannabis inflorescence testing.

Common Change Management Challenges and How to Address Them

No organization, no matter how large or small, is safe from missteps in their efforts to progress and evolve. Mergers and acquisitions are the largest and loftiest of all change efforts a company can set out to achieve, with roughly 70 to 90 percent of them failing abysmally according to the Harvard Business Review. Failure isn’t limited to large-scale change pursuits, though. HBR cites studies that indicate a staggering 60-70 percent rate of failure for all organizational change projects  [Read More]

Robotics + LIMS Software = Win-Win for Manufacturing Labs

With all that’s going on in the world and its economies today, there’s no better time for manufacturers to turn to robotics solutions. From labor shortages and inflated material costs to supply chain backups and a potential recession, manufacturers are faced with many challenges. Those manufacturers who must design, produce, and test their products in controlled laboratory environments are no exception. [Read More]

How ESG Initiatives Are Impacting the Workforce

In recent years, there has been an increased focus on environmental, social, and governance (ESG) issues in the business world. From large corporations to small businesses, more and more organizations are looking for ways to incorporate ESG Initiatives principles into their operations.  But what does this shift mean for the workforce? How are employees responding to these changes – and what does it mean for your business? [Read  More]

Selecting a LIMS? Why Services Are Just as Important as the Product

Whether you’re choosing your first LIMS or thinking of upgrading to a different platform, it’s tempting to focus solely on product features and capabilities. But that’s only looking at part of the equation. It’s equally important to consider the services available for the product through the vendor and/or third parties. [Read More]

How Logilab SDMS helps Laboratories to enable GLP Compliance – Part 3

Logilab SDMS has been designed and demonstrated to be fit for purpose in a GLP environment and introduced in a pre-planned manner. The system’s operational validation process during its original product development as well as any project implementation stage includes requirement specification, design documentation, industry coding standards, unit and system testing processes with test documents and reports. [Read More]

Astrix Announces Landmark PV Preparedness Self-Assessment

Since Pharmacovigilance programs are designed to manage—if not prevent—surprises, preparedness is a focus of enabling vigilance. To support executives tasked with managing their company’s PV and Safety risk, Astrix has developed the first-of-its-kind Program Preparedness Self-Assessment. Just as Open-Source software is code that is designed to be publicly accessible, the Astrix PV Preparedness Self-Assessment is being made freely available for use by the PV/Safety community. [Read More]

Laboratory Informatics Weekly Update – Volume 20, Issue 45

November 9, 2022 Laboratory Informatics Weekly Update Volume 20, Issue 45   In This Issue  Featured Content 11/09/2022 - LIMS Selection Workbook for All LaboratoriesWhen planning a project of any type, it makes perfect sense to initially research and detail the specifics of the project to lay a solid foundation to work from. This is particularly true with software development, where careful initial planning is vital to ensuring the project is legitimate in the eyes of critical stakeholders and will meet specified goals. This demands the creation of a software requirements specification.  Many specification documents for laboratory informatic systems have…

Exploration of organic superionic glassy conductors by process and materials informatics with lossless graph database

Like many other scientific disciplines, materials science is seeing many advances thanks to advanced computer systems that records large volumes of data and analyze it with speed. However, this data capture, analysis, and sharing has its challenges in material science, requiring more sophisticated systems. Hatakeyama-Sato et al. highlight this fact with their materials informatics software platform that "losslessly describes the relationships of structures, properties, and processes as graphs in electronic laboratory notebooks (ELNs)." After describing the impetus for developing the platform, the authors explain its use within the context of materials informatics using a specific use case involving hundreds of experiments related to organic superionic glassy conductors. The authors include the methodology for those experiments and a wealth of supplementary information, while concluding their platform enables direct data sharing of material research, which "will improve scientific communication and accelerate integration of material knowledge."

Informatics in the Environmental Laboratory

Can a laboratory operate successfully without the use of laboratory informatics? To some, the answer is always “yes, informatics makes it easier, but it isn’t a requirement”, and that is true in a technical sense, but in reality, the practical answer is “not anymore”. The use of informatics in the environmental industry is an example we’ll be looking at in this piece.  [Read More]

Got Ideas for Improving Your LIMS? Join Our Labbit UX Research Group

At Semaphore Solutions, we’re conducting UX research for our Labbit Intelligent Lab System, a full order-to-result software solution for molecular diagnostic laboratories. Our goal is to make Labbit one of the best LIMS in the world — from its architecture and infrastructure right through to the user experience. We want your input! [Read More]

The Top Ten Life Science Hubs in the US

The United States is home to some of the world’s leading life science hubs. From Boston to San Francisco, these cities attract top talent and investment dollars in the life sciences sector. Here are ten of the top locations for life science hubs in the United States. [Read More]